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History

Earl W. Davie

Earl Davie, MD, PhD


Spanning more than four decades, the research of Earl Davie, MD, PhD, has elucidated many areas of the coagulation cascade and led to effective treatments for patients with hemophilia. With colleagues, Dr. Davie devised the revolutionary theory that proteins in the blood plasma are activated by minor proteolysis in order for blood to clot and then proceeded to identify and characterize these proteins in detail throughout the 1960s and 70s. Later, with new DNA technologies, he also isolated, sequenced, and expressed the genes for these clotting factors. For these critical achievements, Dr. Davie received the Society's Henry M. Stratton Medal in 1993. He is professor emeritus of biochemistry at the University of Washington in Seattle