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(8 (} A?F/ {eq/( 愂@7xudyBM>/]Ϋwi/OF/Wh98lӎJE iCK%[yEEJۨw:݇ai7 8 uCtN݅t7* -ZA++M5ߙHϏ]/Uw~" 4!@#@ZإBqWA$;.[u)Gz/]<K9 j"0n|s}nw1z߇o2jAɽ7-[j*VyyBvW Ne9J/Z s`gƉ+,.}Xzs3 x #+(xk?m>4kAO,K6)F좁}!9YKaXvKXjZN%]P,js/*u$ ,ȽwLYS,Y\3QYMajA}_5 ]s_G]b߽ȝjZH`?̩7& Bu滖qeN)>_[pL-?ʾ}\܍uV@]D,7̪Ts.FfD)ѩN0nNsn&Ud^NZcW= f\eu'JN^^+$-Mj+p&/7xy_>k BG%]*rmΕq^0 Ѱf[ɍ,Y[cWIŽ]Sř!qQU+b$KL5%Xwl{Q,e K>*鵤ɮʱ簨{6"^ƙ(U*+8ɰ(rbZҹT-/5711~#LJfǥɱ>,k$ezP#ޏ0lO@-PΛ endstream endobj 407 0 obj [0.0 0.0 0.0] endobj 408 0 obj <> endobj 409 0 obj <>/ProcSet[/PDF/ImageB]/XObject<>>>/Subtype/Form>>stream H*w6PH/2433620007V0BdP\!9K3@%+ <N endstream endobj 410 0 obj <> endobj 411 0 obj <> endobj 412 0 obj <> endobj 413 0 obj <>/ExtGState<>>>/Subtype/Form>>stream Hw6PH.V0C<.}wPz1..JJ0E endstream endobj 414 0 obj <>stream 74365493 Deep vein thrombus is a clot that can form in the leg and move to your lungs. 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Red blood corpuscles and drepanocytes. Sick-cell anemia, is a chronic hemolytic anemia. This congenital disease due to the production of an abnormal protein of hemoglobin (hemoglobin S or Hb S), less soluble. This one agregates, and is responsible for the deformation of the red blood corpuscles that take a very recognizable shape in sickle (sickle cells). Thoses red blood corpuscles are rigidified and have lost their capacity to warp, that they cause an occlusion of the blood vessels of smaller caliber, as a consequence ischemic accidents. Recognized as abnormal by the organism, thoses red blood corpuscles are destroyed in the spleen causing a regenerative anemia. This hemoglobinopathy affect mainly populations of Africa. 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Red blood corpuscles and drepanocytes. Sick-cell anemia, is a chronic hemolytic anemia. This congenital disease due to the production of an abnormal protein of hemoglobin (hemoglobin S or Hb S), less soluble. This one agregates, and is responsible for the deformation of the red blood corpuscles that take a very recognizable shape in sickle (sickle cells). Thoses red blood corpuscles are rigidified and have lost their capacity to warp, that they cause an occlusion of the blood vessels of smaller caliber, as a consequence ischemic accidents. Recognized as abnormal by the organism, thoses red blood corpuscles are destroyed in the spleen causing a regenerative anemia. This hemoglobinopathy affect mainly populations of Africa. 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(pެ\ $'t_Le;f$$l+P^D+Pʫc߼;Z}LػFqd+2[^keDT@<0^\սTVt@=K%Rܸʺ݌3t=72K,,26tlpBu*8deyԬ|(.4SD}hSo!a^H%B$V VfW֯n(/{橻Wj"c/I^ܯӌgGEA2m)4Էi#H VY!kۼ.w`] ʍՇ6 0a.cvSNko <;)BvReMrcRuN{V Z0)`E,0=5*%Zn'P"Rd\) 랛c%Ё u5k+5z:{))2nBtє%h*"H`1-1mOPx7 AG!t2 ¿h.W:[=&)A6)/h*uIBX酤v1 LgDg:]ߴ |VP/nSl94laK=_[ wpN^IWk!MkiND':&R2.$cm0W9zlyWl^P00/f vzWC:3%RA Н1^}.!UrPpBSeEqeS0C2}T\ H.HR ׎[>9((cɌԻk06򉳧Êi8Іǰv:&2sAoʴʰ4"R+]kS%&$I+(0ϭUQٳշ!_'裳ɰ֧[q->><.u̠c`r4[-\LN~i11V8U3Cf[-O.M6`' Xp܈x@L v k$mH]Y Z9x }!jT_R&XqӉ8h+zwAtGh$|ޚmr8grvHG}&y)h[oZ!bt^WDwѩ蠙A1[~qNֵdL1|hE ?bXglknԞ㟒MXn T!wܑJ%E( 1gLz \+i'EuOa·%p9HV n}뻨/c(\驆껯g2V0S4HMaԫ L}^Ҝ$)X?Z訴kHlaI3DR#{#+=Rqf5ՈYy*'J)lKf=_eX}/rQZ*_]GXX|-ΕiK]*x!aQkMam4RagONѺMc4 hm[r2@~7/pZw?%8lc=U-cHk,Q$Kv ¥F});% DY?V+VfVj0 >UjApSY2IPg%Z#*^Ns]wD'+bNHshGn׺γUOF3,NE‡~M'm ڞfRGեCê3^w%4*e[eaUcllw⪔-RI%L߷^S%Uƛ 2'B2l[͂`VDckF^!9B<'B(҆k*}dn jV F!AHC*+.mi`񦋘]«k&4Y}IZ6%G'ɍ-a*UܿUՙ3SXUY`}0\*d6 ^A|>t@(2qnpZf̄+3CjIUx?>7 Au/WGk5(pnG>>G BwPz`nQSM,4-㺝!]W\GWw|T/VL6ji,d}#8ԧ.= _M+~}W8]eFSJG5w ׺Fv$ѪG#x髻sD$=QB| UX㫖ޱsccOV/v9W%7) VR z&BlR>CGHun)2PBO FFS5ȶ3֪5W1 G4\N kJռ9T2=Y¾+lѬ)71z*qճsD T)FR?Vh#e*pdܢ Moe`>stream 2Y0386 chronic granulocytic leukemia cml chronic myelogenous leukemia chronic myeloid leukemia leukemia leukaemia cancer pathology medical disease abnormal cell histology micrograph micrography microscopy abnormal myeloid cell myeloid abnormal bone marrow bone marrow white blood cell granuclocyte Copyright (c) Biophoto Associates / Photo Researchers, Inc. Bone marrow in a patient with Chronic Granulocytic Leukemia (also known as chronic myelogenous leukemia). The bone marrow is replaced by myeloid cells in varying stages of differentiation. Chronic granulocytic leukemia is a cancer of the blood or bone marrow characterized by the production of too many myeloid cells in the bone marrow, affecting the development of granulocytes (white blood cells). 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("*2B'I3/U?nL^nvz2#itpD#7zaCOފ!`*@N.MgP ¹Lv% 3v2Zb؜8>qP8HP>#p3o%䴏}4gp3%VOs o@M4n}sJoE~d4}"Uѥ$]sJ^WD萹vEϳO)?ҹvUϳO)z ?+dz4 o؟؅˲]C[%KW.QF1Eۻ xx kS߽oW]<(T*?jǧ)DUO~ԪfY`c|'Us))#݌UTڤZmhEa B[II2HY$R&N endstream endobj 689 0 obj <>stream DA5363 anaemia anaemias anemia anemias anemic art work artwork blood blood cell blood cells blood corpuscle blood corpuscles cardiovascular cardiovascular apparatus cardio-vascular apparatus cardiovascular apparatuses cardio-vascular apparatuses cardio-vascular system cardiovascular systems cardio-vascular systems cell cells cellular congenital condition congenital conditions congenital disease congenital diseases corpuscle corpuscles draw drawing drawings drepanocyte drepanocytes drepanocytic anaemia drepanocytic anemia erythrocyte erythrocytes genetic disease genetic diseases graphic graphics haematological haematology haemoglobin health hematological hematology hemoglobin hereditary disease hereditary diseases hereditary illness hereditary illnesses illustration illustrations medical medicinal medicine medicines orphan disease orphan diseases rare disease rare diseases rare pathologies rare pathology rbc rbc's red red blood cell red blood corpuscle red blood corpuscles red corpuscle red corpuscles reddish science sciences sickle blood cell sickle cell sickle cell anaemia sickle cells sickle-cell anaemias sickle-cell anemia sickle-cell anemias vasculature medical illustration (c) BSIP / Science Source Drepanocytemia, drawing. Red blood corpuscles and drepanocytes. Sick-cell anemia, is a chronic hemolytic anemia. This congenital disease due to the production of an abnormal protein of hemoglobin (hemoglobin S or Hb S), less soluble. This one agregates, and is responsible for the deformation of the red blood corpuscles that take a very recognizable shape in sickle (sickle cells). Thoses red blood corpuscles are rigidified and have lost their capacity to warp, that they cause an occlusion of the blood vessels of smaller caliber, as a consequence ischemic accidents. Recognized as abnormal by the organism, thoses red blood corpuscles are destroyed in the spleen causing a regenerative anemia. This hemoglobinopathy affect mainly populations of Africa. 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1oyhgkY؝~ֈ@42r(O@. ߓvt{PCZZⶳ3ke[[Pl˚Bb0-aJf|FG$T,6!Z-&O]ޫ[kR9)2PV 'i<עDmRZRZɳXVk ` =`ZE5s¡[shb|su TRGŮX*[ y7%Q dI԰J RyWRF6لmwgZ 54:<c+߽X4f!ˊezWxv@(]arS$Kf ܂xUJbSHߢHhHHܼ}^?TQ!;$җ߇&=G8r.b}ܟ/Wfe\ILIi'hNI!I$I$(ITt: hNtK'I:I)RI"Ro:;tHWgczxV-JM y+, IuF8B  eED $1yUQ]D$v9WȖ9WyRv97(eJV*%9Q(IȬk$HI$RI$LtJI"הɒIIIVyQNu0dfRDp?*\W콧B x;N#LIӭc]V3 Y6rmq@]֫='FzfG9gE()c\bDkÏU Uj {MXQʻc6Jp=2_o6Eg1 pH%Xu9B+opf\I))h4Хu*6I< U@Q3jC{[2-qAf~g<8 - T=*$f1hWRN KBdXb% -)'%R'R''dPihJxI4$III$RI$I"-ND>VZu>-lF:J]8_nva9L)17 #ܫBXU{R.P*EDTJQ(d2,md$It$yI2I*LHI$JRI$I$$I%pS H!ee0g9[軟#℅ິ[ ,l cZ^QLz^UQR c"*A--ZoUgҟ#]!Y‚kFJTRdߦz::* 2)-a3]粤mOЯ\xI4 %Pȴ4#d\Ҳn?ku%(х:l`u6OMLJ#yipSpmvJ9E|KU+1-0UP)!TYd flP^ .%h+nݵmpT/uөLuO C1[# ;p]\eM@BkC{{jCJe6{vʲґ+iUsK}imDr;p^-]QFz-7I }:Kc]eD' ߡ(c8:44#ٍ}N8BAٌ02(c NBHc N(JG J(I,!(R%pJ(JU1JxJW Д)BPxXxO $]*9aPfv?zЯO)6G8 j&)CqSqByE#ʁa?H xѮq~7ϟ}U}.<jxN:`*Z7;>+;Zpa=x'F8r2gG>%T)ʉ*hO)bSSTS$%I$*I$JI$I%)$IK$2JRI'IJI$R\L 2D.DV1OӐ,tP-om ?QC *9R6](\%NW+UX% B5w(e[ׂ ܬQN(EOaQJ1_Of@UvyE6QRBtM*O O%,E5QkqpOʚdPJo[9JZyR6ۙMRTG .rP%ky!V"R}wu w)";0!q&SD)g1kX#1^952O.f8|;QLqk{͞mweg9ĒIu%+,s^$Jr1e*$.Q)Q)JddEmI$ZjI$JI$I$)$IJI$RI<$Y<' 8 Dk%1kIFejMZ ]k5`k)[6RSʹmj ۨ><ݧe;\ZC`M" Ӭ yV+fӚ{r i$$ ٛj -#fڙDlq; ]AaL+hPu 5ੈ)!tcy--5 R? lPBcuN o% FVՇc! w+b.pSP58(r5N2Uv&T[()i!e>)ŎCGu=` /wY{J?U@=w'C8 5-f}IC*.xYj)}pK)O52J=7S}pCIzYh)}/l sB >Oo>*⨛ܛy\-w*r#jqGL@N,tZKօQѩQ+Ka6(;Fʧ~Uh}tak4o QT\L%@D((ّrbS"f*)$JI]2I" $-E$I)I$JRI$TI$'I$O %JMV+ZĚԔL N: ]1KU))B{uu dJ5bN]o%}$)v+ع >b)v?c蔽'+M$xc4'&ܯI7=خ9v?cKr^'\g.ŧ9/HO$c+]Or^W?Db)v-OIz%\_C]ص%??b)v-?A??.)v*=Pc};(ݐ Emjr JWtGqwgh~ "ʶ 7;o~J#m#`?~NL#rDQ*ZwK؞4"{a OD-NHY$IK$T endstream endobj 693 0 obj <>stream DA5363 anaemia anaemias anemia anemias anemic art work artwork blood blood cell blood cells blood corpuscle blood corpuscles cardiovascular cardiovascular apparatus cardio-vascular apparatus cardiovascular apparatuses cardio-vascular apparatuses cardio-vascular system cardiovascular systems cardio-vascular systems cell cells cellular congenital condition congenital conditions congenital disease congenital diseases corpuscle corpuscles draw drawing drawings drepanocyte drepanocytes drepanocytic anaemia drepanocytic anemia erythrocyte erythrocytes genetic disease genetic diseases graphic graphics haematological haematology haemoglobin health hematological hematology hemoglobin hereditary disease hereditary diseases hereditary illness hereditary illnesses illustration illustrations medical medicinal medicine medicines orphan disease orphan diseases rare disease rare diseases rare pathologies rare pathology rbc rbc's red red blood cell red blood corpuscle red blood corpuscles red corpuscle red corpuscles reddish science sciences sickle blood cell sickle cell sickle cell anaemia sickle cells sickle-cell anaemias sickle-cell anemia sickle-cell anemias vasculature medical illustration (c) BSIP / Science Source Drepanocytemia, drawing. Red blood corpuscles and drepanocytes. Sick-cell anemia, is a chronic hemolytic anemia. This congenital disease due to the production of an abnormal protein of hemoglobin (hemoglobin S or Hb S), less soluble. This one agregates, and is responsible for the deformation of the red blood corpuscles that take a very recognizable shape in sickle (sickle cells). Thoses red blood corpuscles are rigidified and have lost their capacity to warp, that they cause an occlusion of the blood vessels of smaller caliber, as a consequence ischemic accidents. Recognized as abnormal by the organism, thoses red blood corpuscles are destroyed in the spleen causing a regenerative anemia. This hemoglobinopathy affect mainly populations of Africa. 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Red blood corpuscles and drepanocytes. Sick-cell anemia, is a chronic hemolytic anemia. This congenital disease due to the production of an abnormal protein of hemoglobin (hemoglobin S or Hb S), less soluble. This one agregates, and is responsible for the deformation of the red blood corpuscles that take a very recognizable shape in sickle (sickle cells). Thoses red blood corpuscles are rigidified and have lost their capacity to warp, that they cause an occlusion of the blood vessels of smaller caliber, as a consequence ischemic accidents. Recognized as abnormal by the organism, thoses red blood corpuscles are destroyed in the spleen causing a regenerative anemia. This hemoglobinopathy affect mainly populations of Africa. 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Sickle cell anemia is a painful disease that affects the red blood cells. If a person inherites one copy of the mutation, that person is resistant to the parasite-borne disease malaria. Meanwhile, if two copies of the sickle cell trait is inherited, the genetic mutation of sickle cell anemia is inherited. Magnification-7,400x Eye of Science endstream endobj 789 0 obj <>stream DA5363 anaemia anaemias anemia anemias anemic art work artwork blood blood cell blood cells blood corpuscle blood corpuscles cardiovascular cardiovascular apparatus cardio-vascular apparatus cardiovascular apparatuses cardio-vascular apparatuses cardio-vascular system cardiovascular systems cardio-vascular systems cell cells cellular congenital condition congenital conditions congenital disease congenital diseases corpuscle corpuscles draw drawing drawings drepanocyte drepanocytes drepanocytic anaemia drepanocytic anemia erythrocyte erythrocytes genetic disease genetic diseases graphic graphics haematological haematology haemoglobin health hematological hematology hemoglobin hereditary disease hereditary diseases hereditary illness hereditary illnesses illustration illustrations medical medicinal medicine medicines orphan disease orphan diseases rare disease rare diseases rare pathologies rare pathology rbc rbc's red red blood cell red blood corpuscle red blood corpuscles red corpuscle red corpuscles reddish science sciences sickle blood cell sickle cell sickle cell anaemia sickle cells sickle-cell anaemias sickle-cell anemia sickle-cell anemias vasculature medical illustration (c) BSIP / Science Source Drepanocytemia, drawing. Red blood corpuscles and drepanocytes. Sick-cell anemia, is a chronic hemolytic anemia. This congenital disease due to the production of an abnormal protein of hemoglobin (hemoglobin S or Hb S), less soluble. This one agregates, and is responsible for the deformation of the red blood corpuscles that take a very recognizable shape in sickle (sickle cells). Thoses red blood corpuscles are rigidified and have lost their capacity to warp, that they cause an occlusion of the blood vessels of smaller caliber, as a consequence ischemic accidents. Recognized as abnormal by the organism, thoses red blood corpuscles are destroyed in the spleen causing a regenerative anemia. This hemoglobinopathy affect mainly populations of Africa. 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Colored scanning electron micrograph (SEM) of newly-hatched zebrafish (Danio rerio) young or fry. These fish are used to study embryonic development. The eyes (pink) can be seen in the heads. Zebrafish eggs are transparent. This allows observation of the differentiation of the cells into different body organs. Zebrafish also develop rapidly (2-4 days) and the eggs develop outside the mother's body. As vertebrates, these fish are more appropriate models for some genetics research than fruit flies and nemotode worms. They are cheaper than mice, but not as well understood. Zebrafish are freshwater fish that are found in India. Magnification: x30 when printed 10cm wide. 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Dechorionation of embryos is done prior to staining. The scientist uses a stereomicroscope to view the embryos. 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